Imaging of pituitary tumors: a narrative review of magnetic resonance imaging findings

Authors

DOI:

https://doi.org/10.63688/79rxkd48

Keywords:

Pituitary tumors, Magnetic resonance imaging, Imaging

Abstract

Introduction: Pituitary tumors constitute a heterogeneous group of lesions that may cause hormonal abnormalities and mass effect. Magnetic resonance imaging (MRI) is the imaging method of choice for their evaluation.

Objective: To synthesize the scientific evidence on the main imaging findings of pituitary tumors assessed by MRI.

Methods: A narrative literature review was conducted in PubMed, Scopus, SciELO, and Google Scholar, including publications from January 2020 to March 2026. Fifteen studies directly related to the objective were selected.

Results: The studies demonstrated variations in signal intensity and enhancement patterns, as well as suprasellar extension, cavernous sinus invasion, optic chiasm compression, and the presence of cystic, hemorrhagic, and necrotic components. These findings contribute to the differentiation of various sellar lesions.

Conclusions: Systematic interpretation of MRI improves the characterization of pituitary tumors, supports differential diagnosis, and provides relevant information for therapeutic planning.

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References

Ach, T., Bouzaouech, I., Gasmi, A., Ben Haj Slama, N., Ghachem, A., Abbes, L., Halloul, I., Saafi, W., El Fekih, H., Saad, G., Hasni, Y., & El Mhabrech, H. (2026). The diagnostic challenge of hypophysitis vs. non-functioning pituitary macroadenomas: An updated review and comparative analysis of distinguishing criteria. Diagnostics, 16(2), 328. https://doi.org/10.3390/diagnostics16020328

Asa, S. L., Ezzat, S., & Mete, O. (2025). Clinical integration and application of the 2022 WHO pituitary tumor classification. Neuro-Oncology Advances, 7(Suppl. 1), i10–i16. https://doi.org/10.1093/noajnl/vdae145

Cosgun, Z., Dagistan, Y., Dagistan, E., & Kalfaoglu, M. E. (2026). Neglected giant pituitary adenoma: A unique case report. Journal of Endocrine Systems Research, 1(1), 11–16. https://doi.org/10.64229/ehb2ek06

Dai, C., Kang, J., Liu, X., Yao, Y., Wang, H., & Wang, R. (2021). How to classify and define pituitary tumors: Recent advances and current controversies. Frontiers in Endocrinology, 12, 604644. https://doi.org/10.3389/fendo.2021.604644

Dervişoğlu, E., Altıntaş, C., Çam, İ., Çabuk, B., Anık, İ., Ceylan, S., & Anık, Y. (2022). Discriminative MRI findings of pituitary adenomas from craniopharyngiomas. Sinir Sistemi Cerrahisi Dergisi, 8(3), 94–103. https://doi.org/10.54306/SSCD.2022.216

Fountas, A., Lithgow, K., Loughrey, P. B., Bonanos, E., Shinwari, S. K., Mitchell, K., Mavilakandy, A., Ahsan, M., Matheou, M., Isand, K., Hamblin, R., McLaren, D. S., Ullah, H. Z., Grixti, L., MacFarlane, J., Jayasuriya, A., Bhatti, S., Wunna, W., Shah, S., ... Karavitaki, N. (2025). Conservatively managed non-functioning pituitary macroadenomas: Cohort study from the UK Non-functioning Pituitary Adenoma Consortium. European Journal of Endocrinology, 192(5), 680–690. https://doi.org/10.1093/ejendo/lvaf091

Gaillard, F., Yap, J., & El-Feky, M. (2021). Adamantinomatous craniopharyngioma. Radiopaedia.org. https://doi.org/10.53347/rID-94566

Gaillard, F., Du, D., Knipe, H. (2024). Pituitary microadenoma. Radiopaedia.org. https://doi.org/10.53347/rID-16889

Gaillard, F., Yap, J., Molinari, A. (2025). Pituicytoma. Radiopaedia.org. https://radiopaedia.org/articles/pituicytoma

Iglesias, P. (2025). Histopathological types, clinical presentation, imaging studies, treatment strategies, and prognosis of posterior pituitary tumors: An updated review. Journal of Clinical Medicine, 14(13), 4553. https://doi.org/10.3390/jcm14134553

Li, J., Xia, W., & Wu, M. (2026). Case report: Pediatric ACTH-secreting pituitary adenoma presenting with hypertension and anuria. Frontiers in Endocrinology, 17, 1894223. https://doi.org/10.3389/fendo.2026.1894223

Matarrita Rojas, L. A., Inces Oreamuno, J. J., Zúñiga Arceyut, W. E., Brenes Navarro, K. Y., & Montero Jiménez, M. (2025). Tumores hipofisiarios: Una revisión actualizada. Revista Electrónica de PortalesMedicos.com, 20(16), 882. https://www.revista-portalesmedicos.com/revista-medica/tumores-hipofisiarios-una-revision-actualizada/

Pereira, F. V., Yoshida, N. Y., Soares, D. F., Garmes, H. M., Zantut-Wittmann, D. E., Rogério, F., Dal Fabbro, M., Duarte, J. Á., & Reis, F. (2025). Pituitary macroadenoma: Less common neuroimaging features in a common lesion. Radiologia Brasileira, 58, e20250065. https://doi.org/10.1590/0100-3984.2025.0065

Tsukamoto, T., & Miki, Y. (2023a). Imaging of pituitary tumors: An update with the 5th WHO classifications—Part 2. Neoplasms other than PitNET and tumor-mimicking lesions. Japanese Journal of Radiology, 41(8), 808–829. https://doi.org/10.1007/s11604-023-01407-0

Tsukamoto, T., & Miki, Y. (2023b). Imaging of pituitary tumors: An update with the 5th WHO classifications—Part 1. Pituitary neuroendocrine tumor (PitNET)/pituitary adenoma. Japanese Journal of Radiology, 41(8), 789–806. https://doi.org/10.1007/s11604-023-01400-7

Published

2026-08-30

How to Cite

Lamprea Villegas, M. C., Meza Pincay, D. S., Lema Robalino , D. S., Marcillo Marcillo, J. C., & Barrera Vásquez, A. M. (2026). Imaging of pituitary tumors: a narrative review of magnetic resonance imaging findings. Sage Sphere International Journal Esfera Sabia Revista Internacional, 3(1), 1-16. https://doi.org/10.63688/79rxkd48