Impact of elastography as a diagnostic tool for liver diseases

Authors

DOI:

https://doi.org/10.63688/fxg9nz67

Keywords:

elastography, liver fibrosis, liver diseases

Abstract

Introduction: Liver diseases represent a major health problem and require diagnostic methods capable of identifying fibrosis and disease progression noninvasively. Elastography enables the assessment of liver stiffness using different ultrasound and magnetic resonance imaging techniques.

Objective: To synthesize the available scientific evidence on the impact of elastography as a diagnostic tool for liver diseases, highlighting its main applications, benefits, and clinical utility.

Methodology: A descriptive, qualitative narrative literature review was conducted on scientific publications addressing the use of elastography in liver diseases. PubMed/MEDLINE, Scopus, and SciELO were searched for studies published between 2021 and 2026 in English and Spanish. The information was analyzedusing a narrative synthesis approach. A total of 156 records were identified, 29 duplicates were removed, and 117 publications were excluded for not meeting the selection criteria. Finally, 10 articles were included in the narrative synthesis.

Results: The studies demonstrated the usefulness of transient elastography, point shear wave elastography (pSWE), two-dimensional shear wave elastography (2D-SWE), and magnetic resonance elastography (MRE) for detecting and staging fibrosis, cirrhosis, and steatotic liver disease. Furthermore, liver stiffness was associated with disease severity parameters and the risk of decompensation.

Conclusions: Elastography is a noninvasive diagnostic tool that is useful for the assessment and monitoring of various liver diseases.

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References

Bei, Z., Xiao, Y., Zuo, Z., He, J., Wang, S., & Feng, T. (2026). Ultrasound-based transient elastography combined with metabolic biomarkers enhances the diagnostic efficacy for pediatric MASLD. Medicine, 105(38), e50730. https://doi.org/10.1097/MD.0000000000050730

Duan, M., Sun, Z., Chu, Q., Huang, M., Yao, F., Che, Y., Zhang, Y., Wang, K., & Liu, J. (2026). The diagnostic value of MRE in patients with decompensated cirrhosis: Comparing it to Gd-EOB-DTPA-enhanced MRI. BMC Medical Imaging, 26, 352. https://doi.org/10.1186/s12880-026-02426-9

Elmansy, N., Ali, A. W., Gadalla, A. A. E. H., Hashem, M. B., Al Sehemy, L., Gaber, Y., Yosry, A., & Elnafrawy, M. S. A. E. (2026). A comparative study of color Doppler ultrasonography and transient hepatic elastography (FibroScan) in grading non-alcoholic fatty liver disease patients and assessing hepatic hemodynamics. Egyptian Journal of Radiology and Nuclear Medicine, 57, 38. https://doi.org/10.1186/s43055-026-01706-2

Jafari, S. H., Moradi, S., & Zeinadini Maymand, M. (2026). Comparative assessment of shear wave elastography in patients with splenomegaly due to cirrhosis versus other etiologies. Egyptian Journal of Radiology and Nuclear Medicine, 57, 108. https://doi.org/10.1186/s43055-026-01771-7

Kim, D., Danpanichkul, P., Wijarnpreecha, K., Cholankeril, G., Loomba, R., & Ahmed, A. (2025). Current burden of steatotic liver disease and fibrosis among adults in the United States, 2017–2023. Clinical and Molecular Hepatology, 31(2), 382–393. https://doi.org/10.3350/cmh.2024.0987

Kratzer, W., Binzberger, A., Kauschke, S. G., Dolze, F., Werner, M., Barth, T. F. E., Neubauer, H., Simon, E., Brunner, A. D., Haggenmüller, B., & Haenle, M. M. (2026). Point shear wave elastography for non-invasive detection of advanced fibrosis in metabolic dysfunction-associated steatotic liver disease: A prospective histologically validated study. BMC Gastroenterology, 26, 451. https://doi.org/10.1186/s12876-026-05123-7

Lee, J., Yang, H., Bae, S. H., Yoo, S., Nam, S. W., Yoon, J., Kwon, J. H., & Lee, S. K. (2026). Shear wave elastography combined with ALBI score enhances prediction of hepatic decompensation in chronic liver disease. JHEP Reports, 8(10), 101963. https://doi.org/10.1016/j.jhepr.2026.101963

Man, S., Deng, Y., Ma, Y., Fu, J., Bao, H., Yu, C., Lv, J., Liu, H., Wang, B., & Li, L. (2023). Prevalence of liver steatosis and fibrosis in the general population and various high-risk populations: A nationwide study with 5.7 million adults in China. Gastroenterology, 165(4), 1025–1040. https://doi.org/10.1053/j.gastro.2023.05.053

Mansour, A., Amouei, M., Esmaeili, A. H., Khorasanian, A. S., Gerami, H., Radmard, A. R., Afshinpour, A., Fani Sadrabadi, F. S., Madreseh, E., Mohajeri-Tehrani, M. R., & Sajjadi-Jazi, S. M. (2026). Associations between adiposity indices and liver steatosis and stiffness assessed by two-dimensional shear wave elastography in patients with type 2 diabetes mellitus: A cross-sectional study. BMC Endocrine Disorders, 26, 240. https://doi.org/10.1186/s12902-026-02351-6

Ozturk, A., Olson, M. C., Samir, A. E., & Venkatesh, S. K. (2022). Liver fibrosis assessment: MR and US elastography. Abdominal Radiology, 47(9), 3037–3050. https://doi.org/10.1007/s00261-021-03269-4

Sidhu, P. S., Secil, M., Clevert, D.-A., Lim, A. K. P., Piskunowicz, M., Ricci, P., Fischer, T., Mitkov, V., Cantisani, V., & Ewersten, C. (2026). Non-invasive ultrasound assessment of chronic liver disease: Current position and future directions for a “one-stop” liver ultrasound approach. Insights into Imaging, 17, 120. https://doi.org/10.1186/s13244-026-02279-4

Thorhauge, K. H., Semmler, G., Johansen, S., Lindvig, K. P., Kjærgaard, M., Hansen, J. K., Torp, N., Hansen, C. D., Andersen, P., Hofer, B. S., Gu, W., Israelsen, M., Mandorfer, M., Reiberger, T., Trebicka, J., Thiele, M., & Krag, A. (2024). Using liver stiffness to predict and monitor the risk of decompensation and mortality in patients with alcohol-related liver disease. Journal of Hepatology, 81(1), 23–32. https://doi.org/10.1016/j.jhep.2024.02.019

Uman, N., Chamroonkul, N., Kaewdech, A., & Sripongpun, P. (2026). Discordance between vibration controlled-transient elastography and ultrasound in cirrhosis assessment: Prognostic implications for liver-related events in patients with chronic hepatitis B. Scientific Reports, 16, 15645. https://doi.org/10.1038/s41598-026-45880-9

Yoon, J. S., Lim, K. J., & Hwang, I. T. (2023). Usefulness of two-dimensional shear wave elastography in the assessment of non-alcoholic fatty liver disease in children and adolescents. Scientific Reports, 13, 10062. https://doi.org/10.1038/s41598-023-37281-z

Yuan, J., Xu, X., Yan, F., Qin, Z., Yan, H., Yang, W., & Lin, H. (2026). Development and validation of fat-corrected virtual MR elastography to assess fibrosis stage in metabolic dysfunction-associated steatotic liver disease. Insights into Imaging, 17, 103. https://doi.org/10.1186/s13244-026-02287-4

Published

2026-10-12

How to Cite

Pinargote Santillán, A. L., Alvarado Valdivieso, F. E., Guerrón Molina, A. M., Barrera Vásquez, A. M., & Guzmán León, J. L. (2026). Impact of elastography as a diagnostic tool for liver diseases. Sage Sphere International Journal Esfera Sabia Revista Internacional, 3(1), 1-15. https://doi.org/10.63688/fxg9nz67